The Chromosomes of Afrotheria and Their Bearing on Mammalian Genome Evolution

@article{Svartman2012TheCO,
  title={The Chromosomes of Afrotheria and Their Bearing on Mammalian Genome Evolution},
  author={Marta Svartman and Roscoe Stanyon},
  journal={Cytogenetic and Genome Research},
  year={2012},
  volume={137},
  pages={144 - 153}
}
Afrotheria is the clade of placental mammals that, together with Xenarthra, Euarchontoglires and Laurasiatheria, represents 1 of the 4 main recognized supraordinal eutherian clades. It reunites 6 orders of African origin: Proboscidea, Sirenia, Hyracoidea, Macroscelidea, Afrosoricida and Tubulidentata. The apparently unlikely relationship among such disparate morphological taxa and their possible basal position at the base of the eutherian phylogenetic tree led to a great deal of attention and… 

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References

SHOWING 1-10 OF 82 REFERENCES

Genome Size: A Novel Genomic Signature in Support of Afrotheria

TLDR
It is shown that the GSs of six selected representatives across the Afrotheria supraordinal group are among the highest for the extant Placentalia, providing a novel genomic signature of this enigmatic group that should assist in planning new genome sequencing initiatives.

Phylogenomic data analyses provide evidence that Xenarthra and Afrotheria are sister groups.

TLDR
The phylogenetic analysis joined Xenarthra and Afrotheria on a common branch, Atlantogenata, and this topology was found to fit the data significantly better than the alternative trees, and exceeds by a considerable margin that of any previous study.

Chromosome painting in the manatee supports Afrotheria and Paenungulata

TLDR
The manatee chromosome painting data confirm that the associations 1/19 and 5/21 phylogenetically link afrotherian species and show that Afrotheria is a natural clade.

Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies

TLDR
Evidence is provided that the evolutionary breakpoints that characterise human syntenies detected in the basal Afrotheria correspond at the chromosomal band level with fragile sites and that fragile sites are conserved among afrotherian species.

Molecular phylogeny and divergence times of Malagasy tenrecs: Influence of data partitioning and taxon sampling on dating analyses

TLDR
A timeframe of tenrec evolution built on the basis of this solid phylogenetic framework showed that morphological specializations of the tenrecs may have been affected by environmental changes caused by climatic and/or subsequent colonization events.

A chromosome painting test of the basal Eutherian karyotype

We studied the chromosomes of an Afrotherian species, the short-eared elephant shrew Macroscelides proboscideus with traditional banding techniques and mapped the homology to human chromosomes by

Molecular evidence for multiple origins of Insectivora and for a new order of endemic African insectivore mammals.

The traditional views regarding the mammalian order Insectivora are that the group descended from a single common ancestor and that it is comprised of the following families: Soricidae (shrews),

Chromosome painting among Proboscidea, Hyracoidea and Sirenia: support for Paenungulata (Afrotheria, Mammalia) but not Tethytheria

TLDR
The reconstruction of an ancestral paenungulate karyotype and the estimation of rates of chromosomal evolution indicate a reduced rate of genomic repatterning following the Paenungulata radiation.

Endemic African mammals shake the phylogenetic tree

TLDR
DNA sequences from three mitochondrial genes and two nuclear genes are analysed to examine relationships of insectivores to other mammals and suggest that there was an extensive African radiation from a single common ancestor that gave rise to ecologically divergent adaptive types.

Reciprocal chromosome painting among human, aardvark, and elephant (superorder Afrotheria) reveals the likely eutherian ancestral karyotype

TLDR
The comparative chromosome maps presented between human and these Afrotherian species provide further insight into mammalian genome organization and comparative genomic data for theAfrotheria, one of the four major evolutionary clades postulated for the Eutheria.
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