The Chinese herbal medicine Sophora flavescens activates pregnane X receptor.

Abstract

Sophora flavescens (SF) is an herbal medicine widely used for the treatment of viral hepatitis, cancer, viral myocarditis, gastrointestinal hemorrhage, and skin diseases. It was recently reported that SF up-regulates CYP3A expression. The mechanism of SF-induced CYP3A expression is unknown. In the current study, we tested the hypothesis that SF-induced… (More)
DOI: 10.1124/dmd.110.035253

Topics

6 Figures and Tables

Slides referencing similar topics