The Chemokine CXCL13 Is a Prognostic Marker in Clinically Isolated Syndrome (CIS)

@inproceedings{Brettschneider2010TheCC,
  title={The Chemokine CXCL13 Is a Prognostic Marker in Clinically Isolated Syndrome (CIS)},
  author={Johannes Brettschneider and Anne Czerwoniak and Makbule Senel and Lubin Fang and Jan Kassubek and Elmar H. Pinkhardt and Florian Lauda and Tamara Kapfer and Schloegel. Jesse and Vera Lehmensiek and Albert Christian Ludolph and Markus Otto and Prof. Dr. H. Tumani},
  booktitle={PloS one},
  year={2010}
}
BACKGROUND There is increasing recognition of the importance of B lymphocytes in the immunopathogenesis of multiple sclerosis (MS), encouraging the evaluation of B cell-associated biomarkers in the cerebrospinal fluid (CSF). We aimed to evaluate the relevance of the B cell chemoattractant CXCL13 as a prognostic marker in patients with clinically isolated syndrome (CIS) regarding conversion to MS, and to compare it to Barkhof criteria in magnetic resonance imaging (MRI), oligoclonal bands (OCB… CONTINUE READING

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