The Chemical Composition of Isolated Chromosomes

@article{Mirsky1947TheCC,
  title={The Chemical Composition of Isolated Chromosomes},
  author={A. E. Mirsky and Hans Ris},
  journal={The Journal of General Physiology},
  year={1947},
  volume={31},
  pages={7 - 18}
}
By means of 1 M NaCl isolated lymphocyte chromosomes can be separated into two fractions, each of which contains nucleoprotein. The fraction soluble in M NaCl consists largely of desoxyribose nucleohistone, and constitutes 90 to 92 per cent of the mass of the chromosome. The insoluble residue (the residual chromosome is a coiled thread containing some 12 to 14 per cent of ribose nucleic and about one-fifth as much desoxyribose nucleic acid; the residual chromosome accounts for 8 to 10 per cent… CONTINUE READING
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