The Changing Geometry of a Fitness Landscape Along an Adaptive Walk

@inproceedings{Greene2014TheCG,
  title={The Changing Geometry of a Fitness Landscape Along an Adaptive Walk},
  author={Devin Greene and Kristina Crona},
  booktitle={PLoS Computational Biology},
  year={2014}
}
It has recently been noted that the relative prevalence of the various kinds of epistasis varies along an adaptive walk. This has been explained as a result of mean regression in NK model fitness landscapes. Here we show that this phenomenon occurs quite generally in fitness landscapes. We propose a simple and general explanation for this phenomenon, confirming the role of mean regression. We provide support for this explanation with simulations, and discuss the empirical relevance of our… CONTINUE READING
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