The Cdc14 phosphatase is functionally associated with the Dbf2 protein kinase in Saccharomycescerevisiae

@article{Grandin1998TheCP,
  title={The Cdc14 phosphatase is functionally associated with the Dbf2 protein kinase in Saccharomycescerevisiae},
  author={Nathalie Grandin and Alexandra Almeida and Michel Charbonneau},
  journal={Molecular and General Genetics MGG},
  year={1998},
  volume={258},
  pages={104-116}
}
The Saccharomyces cerevisiae Cdc14 protein phosphatase and Dbf2 protein kinase have been implicated to act during late M phase, but their functions are not known. We report here that CDC14 is a low-copy suppressor of the dbf2-2 mutation at 37° C. The kinase activity of Dbf2 accumulated at a high level, in vivo, during a cdc14 arrest and was also much higher in cdc14 mutant cells at the permissive temperature of growth, therefore in cycling mutant cells than in cycling wild-type cells. This… CONTINUE READING
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