The Catalytic Asymmetric Aldol Reaction.

@article{Machajewski2000TheCA,
  title={The Catalytic Asymmetric Aldol Reaction.},
  author={Machajewski and W Wong},
  journal={Angewandte Chemie},
  year={2000},
  volume={39 8},
  pages={1352-1375}
}
The construction of C-C bonds with complete control of the stereochemical course of a reaction is of utmost importance for organic synthesis. The aldol reaction-the simple addition of an enolate donor to a carbonyl acceptor-is one of the most powerful reactions available to the synthetic chemist. In general, control of the relative and absolute configuration of the newly formed stereogenic centers has been achieved through the use of chiral starting materials or chiral auxiliaries. In recent… CONTINUE READING

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