The Case for an Error Minimizing Standard Genetic Code

@article{Freeland2004TheCF,
  title={The Case for an Error Minimizing Standard Genetic Code},
  author={S. Freeland and Tao Wu and Nick Keulmann},
  journal={Origins of life and evolution of the biosphere},
  year={2004},
  volume={33},
  pages={457-477}
}
Since discovering the pattern by which amino acids are assigned to codons within the standard genetic code, investigators have explored the idea that natural selection placed biochemically similar amino acids near to one another in coding space so as to minimize the impact of mutations and/or mistranslations. The analytical evidence to support this theory has grown in sophistication and strength over the years, and counterclaims questioning its plausibility and quantitative support have yet to… Expand
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