The Cardioprotective Effects of Fish Oil During Pressure Overload Are Blocked by High Fat Intake: Role Of Cardiac Phospholipid Remodeling

@article{Shah2009TheCE,
  title={The Cardioprotective Effects of Fish Oil During Pressure Overload Are Blocked by High Fat Intake: Role Of Cardiac Phospholipid Remodeling},
  author={K. Shah and M. Duda and K. O'Shea and G. Sparagna and David J. Chess and R. Khairallah and Isabelle Robillard‐Frayne and Wenhong Xu and R. Murphy and C. Rosiers and W. Stanley},
  journal={Hypertension},
  year={2009},
  volume={54},
  pages={605-611}
}
  • K. Shah, M. Duda, +8 authors W. Stanley
  • Published 2009
  • Biology, Medicine
  • Hypertension
  • Supplementation with eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from fish oil may prevent development of heart failure through alterations in cardiac phospholipids that favorably impact inflammation and energy metabolism. A high-fat diet may block these effects in chronically stressed myocardium. Pathological left ventricle (LV) hypertrophy was generated by subjecting rats to pressure overload by constriction of the abdominal aorta. Animals were fed: (1) standard diet (10% of… CONTINUE READING
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