The Canonical Notch Signaling Was Involved in the Regulation of Intestinal Epithelial Cells Apoptosis after Intestinal Ischemia/Reperfusion Injury

@inproceedings{Chen2014TheCN,
  title={The Canonical Notch Signaling Was Involved in the Regulation of Intestinal Epithelial Cells Apoptosis after Intestinal Ischemia/Reperfusion Injury},
  author={Guoqing Chen and Zhicao Zhang and Yingdong Cheng and Weidong Xiao and Yuan Qiu and Min Yu and Lihua Sun and Wensheng Wang and Guangsheng Du and Yingchao Gu and Ke Peng and Chao Xu and Hua Yang},
  booktitle={International journal of molecular sciences},
  year={2014}
}
Notch signaling plays a critical role in the maintenance of intestinal homeostasis. The aim of the present study was to investigate the role of Notch signaling in the apoptosis of intestinal epithelial cells after intestinal ischemia reperfusion (I/R) injury. Male C57BL/6 mice were subjected to sham operation or I/R injury. Intestinal tissue samples were collected at 12 h after reperfusion. TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling) staining showed that… CONTINUE READING