The Candida albicans AAA ATPase homologue of Saccharomyces cerevisiae Rix7p (YLL034c) is essential for proper morphology, biofilm formation and activity of secreted aspartyl proteinases.

@article{Melo2006TheCA,
  title={The Candida albicans AAA ATPase homologue of Saccharomyces cerevisiae Rix7p (YLL034c) is essential for proper morphology, biofilm formation and activity of secreted aspartyl proteinases.},
  author={Anderson Sanches Melo and Ana Carolina Barbosa Padovan and Rui C. Serafim and Luciano Puzer and Adriana Karaoglanovic Carmona and Luiz Juliano Neto and Adriana Brunstein and Marcelo R. S. Briones},
  journal={Genetics and molecular research : GMR},
  year={2006},
  volume={5 4},
  pages={664-87}
}
Proper morphology is essential for the ability of Candida albicans to switch between yeast and hyphae and thereby sustain its virulence. Here we identified, by differential screening, a novel C. albicans AAA ATPase encoding gene, CaYLL34 (RIX7), with enhanced expression in hyphae. Phylogenetic analysis suggests that CaYLL34 belongs to a "VCP-like" subgroup… CONTINUE READING