The Cancer Drugs Fund: A Systematic Analysis of the Requirements For Inclusion on the English National List of Drugs for Priority Funding.

CONCLUSIONS • Scoring ≥2 on the CDF scorecard seems to be the key clinical threshold for CDF approval • Most drugs score -1 for toxicity and 0 for both QoL and unmet need • This means that 3 efficacy points are required, which can be achieved in Phase III data from either a • 2-3 month improvement in OS AND PFS, OR • ≥ 4 month improvement in OS OR PFS… (More)