The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture. Recent studies on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate: are essential fatty acids more aptly named indispensable or conditionally dispensable fatty acids?

@article{Cunnane1996TheCS,
  title={The Canadian Society for Nutritional Sciences 1995 Young Scientist Award Lecture. Recent studies on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate: are essential fatty acids more aptly named indispensable or conditionally dispensable fatty acids?},
  author={Stephen C. Cunnane},
  journal={Canadian journal of physiology and pharmacology},
  year={1996},
  volume={74 6},
  pages={629-39}
}
Recent research on the synthesis, beta-oxidation, and deficiency of linoleate and alpha-linolenate raises questions about whether the term essential fatty acid is outdated. Linoleate and alpha-linolenate can be synthesized from their respective 16-carbon precursors, which are present in the human diet; whether the rate of conversion and dietary supply of the precursors are sufficient depends on the actual requirement for linoleate and alpha-linolenate. Pure deficiency of linoleate (diet… CONTINUE READING

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