The Can-SAD study: a randomized controlled trial of the effectiveness of light therapy and fluoxetine in patients with winter seasonal affective disorder.

@article{Lam2006TheCS,
  title={The Can-SAD study: a randomized controlled trial of the effectiveness of light therapy and fluoxetine in patients with winter seasonal affective disorder.},
  author={R. Lam and A. Levitt and R. Levitan and M. Enns and R. Morehouse and E. Michalak and E. Tam},
  journal={The American journal of psychiatry},
  year={2006},
  volume={163 5},
  pages={
          805-12
        }
}
OBJECTIVE Light therapy and antidepressants have shown comparable efficacy in separate studies of seasonal affective disorder treatment, but few studies have directly compared the two treatments. This study compared the effectiveness of light therapy and an antidepressant within a single trial. METHOD This double-blind, randomized, controlled trial was conducted in four Canadian centers over three winter seasons. Patients met DSM-IV criteria for major depressive disorder with a seasonal… Expand
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Quality of life as an outcome indicator in patients with seasonal affective disorder: results from the Can-SAD study
TLDR
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A randomized controlled trial of cognitive-behavioral therapy, light therapy, and their combination for seasonal affective disorder.
TLDR
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Light Therapy for Seasonal and Nonseasonal Depression: Efficacy, Protocol, Safety, and Side Effects
TLDR
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Winter depression recurrence one year after cognitive-behavioral therapy, light therapy, or combination treatment.
TLDR
An intent-to-treat analysis of outcomes during the subsequent winter season using participants randomized to CBT, light therapy, and combination treatment across pilot studies suggests CBT could represent a more effective, practical, and palatable approach to long-term SAD management than light therapy. Expand
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