The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions.

@article{Avery1993TheCE,
  title={The Caenorhabditis elegans unc-31 gene affects multiple nervous system-controlled functions.},
  author={Leon Avery and Cornelia I Bargmann and H Robert Horvitz},
  journal={Genetics},
  year={1993},
  volume={134 2},
  pages={455-64}
}
We have devised a method for selecting Caenorhabditis elegans mutants that execute feeding motions in the absence of food. One mutation isolated in this way is an allele of the gene unc-31, first discovered by S. Brenner in 1974, because of its effects on locomotion. We find that strong unc-31 mutations cause defects in four functions controlled by the nervous system. Mutant worms are lethargic, feed constitutively, are defective in egg-laying and produce dauer larvae that fail to recover. We… CONTINUE READING

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