The Caenorhabditis elegans Lifespan Machine

@article{Stroustrup2013TheCE,
  title={The Caenorhabditis elegans Lifespan Machine},
  author={Nicholas Stroustrup and Bryne Ulmschneider and Zachary M. Nash and Isaac F. L{\'o}pez-Moyado and Javier Apfeld and Walter Fontana},
  journal={Nature Methods},
  year={2013},
  volume={10},
  pages={665-670}
}
  • Nicholas Stroustrup, Bryne Ulmschneider, +3 authors Walter Fontana
  • Published in Nature Methods 2013
  • Biology, Medicine
  • The measurement of lifespan pervades aging research. Because lifespan results from complex interactions between genetic, environmental and stochastic factors, it varies widely even among isogenic individuals. The actions of molecular mechanisms on lifespan are therefore visible only through their statistical effects on populations. Indeed, survival assays in Caenorhabditis elegans have provided critical insights into evolutionarily conserved determinants of aging. To enable the rapid… CONTINUE READING

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