The Ca2+ affinity of the plasma membrane Ca2+ pump is controlled by alternative splicing.

Abstract

The plasma membrane Ca2+ pump is a calmodulin-regulated P-type ATPase that is an essential element in controlling intracellular Ca2+ concentration. Studies on the gene structure of this pump have revealed an alternate splice option that changes the structure of the calmodulin-binding domain. This change in the structure of the enzyme results in a reduced… (More)

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Cite this paper

@article{Enyedi1994TheCA, title={The Ca2+ affinity of the plasma membrane Ca2+ pump is controlled by alternative splicing.}, author={Agnes Enyedi and A. K. Verma and Ruth A. Heim and Hugo Pedro Adamo and Adelaida G. Filoteo and Erwin Strehler and Joelle Penniston}, journal={The Journal of biological chemistry}, year={1994}, volume={269 1}, pages={41-3} }