The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases.

@article{Hurley2005TheCP,
  title={The Ca2+/calmodulin-dependent protein kinase kinases are AMP-activated protein kinase kinases.},
  author={Rebecca L Hurley and Kristin A. Anderson and Jeanne M. Franzone and Bruce E. Kemp and Anthony R. Means and Lee Alan Witters},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 32},
  pages={29060-6}
}
The AMP-activated protein kinase (AMPK) is an important regulator of cellular metabolism in response to metabolic stress and to other regulatory signals. AMPK activity is absolutely dependent upon phosphorylation of AMPKalphaThr-172 in its activation loop by one or more AMPK kinases (AMPKKs). The tumor suppressor kinase, LKB1, is a major AMPKK present in a variety of tissues and cells, but several lines of evidence point to the existence of other AMPKKs. We have employed three cell lines… CONTINUE READING
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