The CYP2C19 enzyme polymorphism.

  title={The CYP2C19 enzyme polymorphism.},
  author={Peter J. Wedlund},
  volume={61 3},
The genetic test is gradually replacing probe drugs as the primary tool for screening populations for the CYP2C19 polymorphism. A full appreciation for the clinical and toxicological relevance of this genetic variation is presently limited. Further research is needed in several areas. The development and use of 3-D models of the CYP2C19 enzyme to automate and increase the rate at which CYP2C19 substrates are identified could reap great benefits. Meanwhile, clinical research should begin to… CONTINUE READING

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