The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity.

@article{Addison2000TheCC,
  title={The CXC chemokine receptor 2, CXCR2, is the putative receptor for ELR+ CXC chemokine-induced angiogenic activity.},
  author={Christina L Addison and Thomas O. Daniel and Marie D. Burdick and Hongtao Liu and Jan Erik Ehlert and Ying Ying Xue and Lilian B{\"u}chi and Andrea Walz and Ann Richmond and Robert M. Strieter},
  journal={Journal of immunology},
  year={2000},
  volume={165 9},
  pages={5269-77}
}
We have previously shown that members of the ELR(+) CXC chemokine family, including IL-8; growth-related oncogenes alpha, beta, and gamma; granulocyte chemotactic protein 2; and epithelial neutrophil-activating protein-78, can mediate angiogenesis in the absence of preceding inflammation. To date, the receptor on endothelial cells responsible for chemotaxis and neovascularization mediated by these ELR(+) CXC chemokines has not been determined. Because all ELR(+) CXC chemokines bind to CXC… CONTINUE READING
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Molecular characterization of receptors for human interleukin - 8 , GRO / melanoma growth - stimulatory activity and neutrophil activating peptide - 2

  • S. B. Morris, Y. Y. Xue, M. D. Burdick, M. S. Mulligan, M. D. Iannettoni, R. M. Strieter
  • Mol . Immunol .
  • 2000

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