The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study.

@article{Bolton2011TheCG,
  title={The CRP genotype, serum levels and lung function in men: the Caerphilly Prospective Study.},
  author={Charlotte E. Bolton and Wiebke Schumacher and John R. Cockcroft and Nicholas J. Timpson and George Davey Smith and John Gallacher and Anne Rumley and Gordon D. O. Lowe and Shah Ebrahim and Dennis J Shale and Y Ben-Shlomo},
  journal={Clinical science},
  year={2011},
  volume={120 8},
  pages={347-55}
}
Systemic CRP (C-reactive protein) has been associated with impaired lung function. A causal relationship would increase the value of CRP as both a diagnostic and therapeutic tool. We assessed the association between lung function parameters, circulating CRP and CRP polymorphisms using Mendelian randomization in efforts to attribute causality to known associations. Spirometric parameters of FEV1 (forced expiratory volume in 1 s) and FVC (forced vital capacity) were determined in 2173 men… CONTINUE READING

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Spirometric parameters of FEV1 ( forced expiratory volume in 1 s ) and FVC ( forced vital capacity ) were determined in 2173 men participating in the Caerphilly Prospective Study .
Serum CRP levels were measured at baseline , and three CRP polymorphisms were analysed .
Serum CRP levels were measured at baseline , and three CRP polymorphisms were analysed .
Serum CRP levels were measured at baseline , and three CRP polymorphisms were analysed .
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