The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder

@inproceedings{Lonsdorf2010TheCP,
  title={The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder},
  author={Tina B. Lonsdorf and Christian R{\"u}ck and Jan Bergstr{\"o}m and Gerhard Andersson and Arne {\"O}hman and Nils Lindefors and Martin Schalling},
  booktitle={BMC psychiatry},
  year={2010}
}
BACKGROUND Cognitive behavioral therapy (CBT) represents a learning process leading to symptom relief and resulting in long-term changes in behavior. CBT for panic disorder is based on exposure and exposure-based processes can be studied in the laboratory as extinction of experimentally acquired fear responses. We have recently demonstrated that the ability to extinguish learned fear responses is associated with a functional genetic polymorphism (COMTval158met) in the COMT gene and this study… CONTINUE READING

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