The CLU Gene rs11136000 Variant is Significantly Associated with Alzheimer’s Disease in Caucasian and Asian Populations

@article{Liu2013TheCG,
  title={The CLU Gene rs11136000 Variant is Significantly Associated with Alzheimer’s Disease in Caucasian and Asian Populations},
  author={Guiyou Liu and Haiyang Wang and Jiafeng Liu and Jingbo Li and Hali Li and Guoda Ma and Yongshuai Jiang and Zugen Chen and Bin Zhao and Keshen Li},
  journal={NeuroMolecular Medicine},
  year={2013},
  volume={16},
  pages={52-60}
}
Large-scale genomewide association studies have reported that the CLU rs11136000 polymorphism is significantly associated with Alzheimer’s disease (AD) in people of Caucasian ancestry. Recently, this association was investigated in Asian populations (Chinese, Japanese, and Korean). However, these studies reported either a weak association or no association between the rs11136000 polymorphism and AD. We believe that this discrepancy may be caused by the relatively small sample size of the… CONTINUE READING
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