The CIMT-monitoring panel: a two-step approach to harmonize the enumeration of antigen-specific CD8+ T lymphocytes by structural and functional assays

@article{Britten2007TheCP,
  title={The CIMT-monitoring panel: a two-step approach to harmonize the enumeration of antigen-specific CD8+ T lymphocytes by structural and functional assays},
  author={Cedrik M. Britten and C{\'e}cile Gouttefangeas and Marij J. P. Welters and Graham P Pawelec and Sven Dominik Koch and Christian H Ottensmeier and Ann Mander and Steffen Walter and Annette Paschen and Jan Mueller-Berghaus and Inge Haas and Andreas Mackensen and Tania T. K\ollgaard and Per Thor Straten and Michael Schmitt and Krzysztof Giannopoulos and Reinhard Maier and Hendrik Veelken and Cristina Bertinetti and Abdo Konur and Christoph Huber and Stefan Stevanovi{\'c} and Thomas Woelfel and Sjoerd H van der Burg},
  journal={Cancer Immunology, Immunotherapy },
  year={2007},
  volume={57},
  pages={289 - 302}
}
The interpretation of the results obtained from immunomonitoring of clinical trials is a difficult task due to the variety of methods and protocols available to detect vaccine-specific T-cell responses. This heterogeneity as well as the lack of standards has led to significant scepticism towards published results. In February 2005, a working group was therefore founded under the aegis of the Association for Immunotherapy of Cancer (“CIMT”) in order to compare techniques and protocols applied… CONTINUE READING

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