The CHILD syndrome. Histologic and ultrastructural studies.

  title={The CHILD syndrome. Histologic and ultrastructural studies.},
  author={Adelaide Ann Hebert and Nancy B. Esterly and Karen A. Holbrook and Jocelyn C Hall},
  journal={Archives of dermatology},
  volume={123 4},
A 4 1/2-month-old female infant had cutaneous and musculoskeletal changes consistent with the diagnosis of congenital hemidysplasia with ichthyosiform erythroderma and limb defects (CHILD) syndrome. This syndrome encompasses abnormalities of several organ systems, and its origins and pathogenesis are poorly understood. This report describes an additional patient with this uncommon syndrome and includes light and electron microscopic studies of her skin lesions. Our patient's clinical features… CONTINUE READING