The CDK inhibitors in cancer research and therapy

@article{Cicenas2011TheCI,
  title={The CDK inhibitors in cancer research and therapy},
  author={Jonas Cicenas and Mindaugas Valius},
  journal={Journal of Cancer Research and Clinical Oncology},
  year={2011},
  volume={137},
  pages={1409-1418}
}
Chemical compounds that interfere with an enzymatic function of kinases are useful for gaining insight into the complicated biochemical processes in mammalian cells. Cyclin-dependent kinases (CDK) play an essential role in the control of the cell cycle and/or proliferation. These kinases as well as their regulators are frequently deregulated in different human tumors. Aberrations in CDK activity have also been observed in viral infections, Alzheimer’s, Parkinson’s diseases, ischemia and some… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 70 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 95 references

The potential role of EGFR/ErbB2 heterodimer in breast cancer

  • J Cicenas
  • Expert opinion Ther Patents 17(6):607–616
  • 2007
Highly Influential
7 Excerpts

Similar Papers

Loading similar papers…