The CDC6 gene is required for centromeric, episomal, and 2-microns plasmid stability in the yeast Saccharomyces cerevisiae.

@article{Storici1995TheCG,
  title={The CDC6 gene is required for centromeric, episomal, and 2-microns plasmid stability in the yeast Saccharomyces cerevisiae.},
  author={F Storici and Jacques Oberto and Carlo V. Bruschi},
  journal={Plasmid},
  year={1995},
  volume={34 3},
  pages={184-97}
}
Temperature-sensitive Saccharomyces cerevisiae cdc6 mutants, under restrictive conditions, show an increase in recombination frequency, as well as chromosome and circular minichromosome loss. The role of the essential CDC6 gene was tested in trans and in cis to study circular plasmid stability. It was possible to demonstrate that the product of the CDC6… CONTINUE READING