The CD5+ B-cell.

  title={The CD5+ B-cell.},
  author={Mariella Dono and Giannamaria Cerruti and Simona Zupo},
  journal={The international journal of biochemistry & cell biology},
  volume={36 11},
In the last two decades, many efforts have been made to better understand the biology of B-lymphoproliferative disorders through the knowledge of physiology and function of the postulated normal counterpart. The follicular mantle B-cells express a typical CD23+ IgM+ IgD+ phenotype and surround the germinal center area in secondary lymphoid organs. CD5+ B-cells with FM phenotype can be isolated from different sources and all share similar morphologic, phenotypic and functional features (small… CONTINUE READING