The CD34 epitope is expressed in neoplastic and malformative lesions associated with chronic, focal epilepsies

@article{Blmcke1999TheCE,
  title={The CD34 epitope is expressed in neoplastic and malformative lesions associated with chronic, focal epilepsies},
  author={Ingmar Bl{\"u}mcke and K. Giencke and Eva Wardelmann and Stefan Beyenburg and Thomas Kral and Nanette M E Sarioglu and Torsten Pietsch and Helmut K. Wolf and Johannes Schramm and Christian Erich Elger and Otmar Dieter Wiestler},
  journal={Acta Neuropathologica},
  year={1999},
  volume={97},
  pages={481-490}
}
The etiology and pathogenesis of complex focal lesions associated with chronic, intractable epilepsy are largely unknown. Some data indicate that malformative changes of the central nervous system may preceed the development of gangliogliomas and other epilepsy-associated neoplasms. In the present immunhistochemical study, we have examined epilepsy-associated lesions for CD34, a stem cell marker transiently expressed during early neurulation. Surprisingly, most tissue samples from patients with… CONTINUE READING

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