The CD19 compartment in myeloma includes a population of clonal cells persistent after high-dose treatment.


Peripheral blood-localized clonal cells in patients with multiple myeloma (MM) have been reported to be insensitive to chemotherapy and it has been suggested that these cells may include the proliferative compartment in myeloma. In this study, circulating clonal CD19+ cells levels were determined in 10 patients with MM by performing patient-specific RT-PCR… (More)