The CD19/CD21 signal transduction complex of B lymphocytes.

  title={The CD19/CD21 signal transduction complex of B lymphocytes.},
  author={Thomas F. Tedder and Lin J Zhou and Pablo Engel},
  journal={Immunology today},
  volume={15 9},
CD19 and CD21 are B-cell surface molecules that associate with each other and with CD81 and Leu-13 to generate a signal transduction complex that is independent of the antigen receptor. Current studies, reviewed here by Thomas Tedder, Liang-Ji Zhou and Pablo Engel, indicate an important biological role for this protein complex in the regulation of B-cell development and activation. 

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