The CD 85 J / Leukocyte Inhibitory Receptor-1 Distinguishes between Conformed and 2-Microglobulin-Free HLA-G Molecules 1

@inproceedings{GonenGross2005TheC8,
  title={The CD 85 J / Leukocyte Inhibitory Receptor-1 Distinguishes between Conformed and 2-Microglobulin-Free HLA-G Molecules 1},
  author={Tsufit Gonen-Gross and Hagit Achdout and Tal I. Arnon and Roi Gazit and Noam Stern and V{\'a}clav Hořej{\vs}ı́ and Debra Goldman-Wohl and Simcha Yagel and Ofer Mandelboim},
  year={2005}
}
For a proper development of the placenta, maternal NK cells should not attack the fetal extravillous cytotrophoblast cells. This inhibition of maternal NK cells is partially mediated via the nonclassical MHC class I molecule HLA-G. Recently, we demonstrated that HLA-G forms disulfide-linked high molecular complexes on the surface of transfected cells. In the present study, we demonstrate that HLA-G must associate with 2m for its interaction with CD85J/leukocyte Ig-like receptor-1 (LIR-1… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

References

Publications referenced by this paper.
Showing 1-10 of 69 references

Similar Papers

Loading similar papers…