The CCN family of proteins: structure–function relationships

@inproceedings{Holbourn2008TheCF,
  title={The CCN family of proteins: structure–function relationships},
  author={Kenneth P. Holbourn and K Ravi Acharya and Bernard V. Perbal},
  booktitle={Trends in biochemical sciences},
  year={2008}
}
The CCN proteins are key signalling and regulatory molecules involved in many vital biological functions, including cell proliferation, angiogenesis, tumourigenesis and wound healing. How these proteins influence such a range of functions remains incompletely understood but is probably related to their discrete modular nature and a complex array of intra- and inter-molecular interactions with a variety of regulatory proteins and ligands. Although certain aspects of their biology can be… CONTINUE READING

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