The CART (Cocaine- and Amphetamine-Regulated Transcript) System in Appetite and Drug Addiction

@article{Vicentic2007TheC,
  title={The CART (Cocaine- and Amphetamine-Regulated Transcript) System in Appetite and Drug Addiction},
  author={A. Vicentic and D. Jones},
  journal={Journal of Pharmacology and Experimental Therapeutics},
  year={2007},
  volume={320},
  pages={499 - 506}
}
  • A. Vicentic, D. Jones
  • Published 2007
  • Psychology, Medicine
  • Journal of Pharmacology and Experimental Therapeutics
  • CART (cocaine- and amphetamine-regulated transcript) peptides are neuromodulators that are involved in feeding, drug reward, stress, cardiovascular function, and bone remodeling. CART peptides are abundant but discretely distributed in the brain, pituitary and adrenal glands, pancreas, and gut. High expression of CART in discrete hypothalamic nuclei associated with feeding has led to behavioral and pharmacological studies that strongly support an anorectic action of CART in feeding. Subsequent… CONTINUE READING
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