The C1473G polymorphism in the Tryptophan hydroxylase-2 gene: involvement in ethanol-related behavior in mice.

Abstract

Tryptophan hydroxylase-2 (Tph2) is the rate limiting enzyme of serotonin synthesis in the brain. The functional (C1473G) polymorphism in the mouse Tph2 gene affecting the enzymatic activity was suspected to be involved in behavioral actions of ethanol (EtOH). Congenic B6-1473C (C/C) and B6-1473G (G/G) lines bred from C57BL/6 mice were not different in EtOH… (More)
DOI: 10.1016/j.neulet.2015.01.043

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@article{Bazovkina2015TheCP, title={The C1473G polymorphism in the Tryptophan hydroxylase-2 gene: involvement in ethanol-related behavior in mice.}, author={Darya V. Bazovkina and Daria V. Lichman and Alexander V. Kulikov}, journal={Neuroscience letters}, year={2015}, volume={589}, pages={79-82} }