The C-terminal region of the Vibrio fischeri LuxR protein contains an inducer-independent lux gene activating domain.

@article{Choi1991TheCR,
  title={The C-terminal region of the Vibrio fischeri LuxR protein contains an inducer-independent lux gene activating domain.},
  author={Seongc Ho Choi and E Peter Greenberg},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1991},
  volume={88 24},
  pages={11115-9}
}
The Vibrio fischeri luminescence genes are activated by an autoinducer and the 250-amino acid residue LuxR protein. To develop a general view of LuxR structure and function, a set of luxR 5'-deletion mutations was generated. Ten luxR mutant plasmids encoding active LuxR proteins with deletions ranging from residues 2-5 (delta 2-5) to residues 2-182 (delta 2-182) were studied. The degree of transcriptional activation of luminescence genes by the truncated LuxR proteins ranged from 0.01% to… CONTINUE READING

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