The C-H Peripheral Stalk Base: A Novel Component in V1-ATPase Assembly

@article{Hildenbrand2010TheCP,
  title={The C-H Peripheral Stalk Base: A Novel Component in V1-ATPase Assembly},
  author={Zacariah L. Hildenbrand and Sudheer Kumar Molugu and Daniela Stock and Ricardo A Bernal},
  journal={PLoS ONE},
  year={2010},
  volume={5}
}
Vacuolar ATPases (V-ATPases) are molecular machines responsible for creating electrochemical gradients and preserving pH-dependent cellular compartments by way of proton translocation across the membrane. V-ATPases employ a dynamic rotary mechanism that is driven by ATP hydrolysis and the central rotor stalk. Regulation of this rotational catalysis is the result of a reversible V1Vo-domain dissociation that is required to preserve ATP during instances of cellular starvation. Recently the method… 
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