The C‐type lectin‐like domain superfamily

@article{Zelensky2005TheCL,
  title={The C‐type lectin‐like domain superfamily},
  author={Alex N. Zelensky and Jill E. Gready},
  journal={The FEBS Journal},
  year={2005},
  volume={272}
}
The superfamily of proteins containing C‐type lectin‐like domains (CTLDs) is a large group of extracellular Metazoan proteins with diverse functions. The CTLD structure has a characteristic double‐loop (‘loop‐in‐a‐loop’) stabilized by two highly conserved disulfide bridges located at the bases of the loops, as well as a set of conserved hydrophobic and polar interactions. The second loop, called the long loop region, is structurally and evolutionarily flexible, and is involved in Ca2+‐dependent… 
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