The Bridging Integrator 1 Gene Polymorphism rs744373 and the Risk of Alzheimer’s Disease in Caucasian and Asian Populations: An Updated Meta-Analysis

@article{Zhu2016TheBI,
  title={The Bridging Integrator 1 Gene Polymorphism rs744373 and the Risk of Alzheimer’s Disease in Caucasian and Asian Populations: An Updated Meta-Analysis},
  author={Ruixia Zhu and Xu Wen Liu and Zhiyi He},
  journal={Molecular Neurobiology},
  year={2016},
  volume={54},
  pages={1419-1428}
}
Recent genome-wide association studies have identified an association between the bridging integrator 1 gene (BIN1) rs744373 polymorphism and late-onset Alzheimer’s disease (LOAD) in individuals of European ancestry. Additionally, a number of studies have focused on the association between rs744373 and Alzheimer’s disease in Caucasian and East Asian populations. However, these results remain inconclusive because of the relatively small sample sizes investigated. Here, we reevaluated this… CONTINUE READING

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