The Brf and TATA-binding protein subunits of the RNA polymerase III transcription factor IIIB mediate position-specific integration of the gypsy-like element, Ty3.

@article{Yieh2000TheBA,
  title={The Brf and TATA-binding protein subunits of the RNA polymerase III transcription factor IIIB mediate position-specific integration of the gypsy-like element, Ty3.},
  author={Lynn Yieh and George A. Kassavetis and E. Peter Geiduschek and Suzanne B. Sandmeyer},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 38},
  pages={29800-7}
}
Ty3 integrates into the transcription initiation sites of genes transcribed by RNA polymerase III. It is known that transcription factors (TF) IIIB and IIIC are important for recruiting Ty3 to its sites of integration upstream of tRNA genes, but that RNA polymerase III is not required. In order to investigate the respective roles of TFIIIB and TFIIIC, we have developed an in vitro integration assay in which Ty3 is targeted to the U6 small nuclear RNA gene, SNR6. Because TFIIIB can bind to the… CONTINUE READING
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Specific Integration Mediated by TFIIIB9

  • Lynn Yieh, George Kassavetis, E. Peter Geiduschek, B Suzanne
  • J. Biol. Chem. 10.1074/jbc.M003149200
  • 1995

1414–1424 2 M. Aye, personal communication. Ty3: Specific Integration Mediated by TFIIIB9 29806 by gest on N ovem er 17

  • L. J. Hansen, D. L. Chalker, K. J. Orlinsky, S. B. Sandmeyer
  • J. Virol
  • 1992
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