The Bovine Mx1 Gene: Characterization of the Gene Structure, Alternative Splicing, and Promoter Region

@article{Kojima2003TheBM,
  title={The Bovine Mx1 Gene: Characterization of the Gene Structure, Alternative Splicing, and Promoter Region},
  author={Takatoshi Kojima and Kazunaga Oshima and Hiroko Watanabe and Masanori Komatsu},
  journal={Biochemical Genetics},
  year={2003},
  volume={41},
  pages={375-390}
}
The Mx gene encodes an antiviral protein and is induced by type I interferons (IFNs). In this study, a new bovine Mx gene (designated Mx1B) was isolated from the endometrial cDNA library of the early pregnant cow. Although the Mx1B cDNA contained a single open reading frame (ORF) the same as the known Mx1, the 5′ untranslated region (UTR) and 5′ coding region of Mx1B were rather different from the corresponding regions of Mx1 Genomic structure analysis revealed that bovine Mx1B was an… CONTINUE READING