The Bound Structures of 17β-Estradiol-Binding Aptamers.

Abstract

DNA aptamers can exhibit high affinity and selectivity towards their targets, but the aptamer-target complex structures are rarely available from crystallography and often difficult to elucidate. This is particularly true of small molecule targets, including 17β-estradiol (E2), which is becoming one of the most widely encountered endocrine-disrupting… (More)
DOI: 10.1002/cphc.201700363

Topics

  • Presentations referencing similar topics