The Bologna criteria for the definition of poor ovarian responders: is there a need for revision?

@article{Ferraretti2014TheBC,
  title={The Bologna criteria for the definition of poor ovarian responders: is there a need for revision?},
  author={Anna Pia Ferraretti and Luca Gianaroli},
  journal={Human reproduction},
  year={2014},
  volume={29 9},
  pages={
          1842-5
        }
}
The Bologna criteria were published by the European Society of Human Reproduction and Embryology (ESHRE) in 2011 to help address the lack of a clear definition of poor ovarian responders. Since its publication, aspects of the criteria have been cited several times, whilst others have been criticized. In this debate, we re-examine the criteria (which address age, the number of oocytes retrieved and the results of ovarian reserve tests) following new evidence produced and we analyse the criticism… 
The Bologna criteria for poor ovarian response: a contemporary critical appraisal
TLDR
Although antral follicle count and anti-Müllerian hormone, are considered good predictors of ovarian reserve, their threshold values are still not universally standardized and high scale studies to validate these criteria are still missing while recent evidence raises concern regarding over diagnosis.
A retrospective evaluation of prognosis and cost-effectiveness of IVF in poor responders according to the Bologna criteria.
TLDR
The use of the Bologna criteria for poor responders is recommended when designing future studies on poor responders and independent validations are warranted prior to concluding that IVF is not cost-effective.
Bologna criteria are predictive for ovarian response and live birth in subsequent ovarian stimulation cycles
TLDR
The results of this study show that the Bologna criteria are clinically relevant in terms of prediction of ovarian response and clinical outcome in subsequent OS cycles.
What is new in the management of poor ovarian response in IVF?
TLDR
DuoStim is the most promising approach to increase the number of oocytes collected in a single ovarian cycle; however, more embryological and clinical data is required, as well as an analysis of its cost-effectiveness.
Age is a major prognosticator in extremely low oocyte retrieval cycles.
Is corifollitropin alfa effective in controlled ovarian stimulation among all poor ovarian responders? A retrospective comparative study
  • A. Andrisani, L. Marin, +8 authors G. Ambrosini
  • Biology, Medicine
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
  • 2019
TLDR
Corifollitropin alfa may be as effective as daily gonadotropins in POR with AFC with AFC > 5 undergoing COS, while it might be inferior to daily gonads in PORN with AFC.
Ovarian stimulation modalities in poor responders
  • Z. Özkan
  • Medicine
    Turkish journal of medical sciences
  • 2019
TLDR
The studies performed for improving cycle outcome in POR cases were evaluated, their notable results were presented, and the encouraging methods applied to improve cycle outcome were presented.
Double Stimulation in the Same Ovarian Cycle (DuoStim) to Maximize the Number of Oocytes Retrieved From Poor Prognosis Patients: A Multicenter Experience and SWOT Analysis
TLDR
A summary of the putative advantages and disadvantages of DuoStim was reported here through a Strengths–Weaknesses–Opportunities–Threats analysis: the strengths of this approach make it very promising, however, more studies are needed in the future to limit its weaknesses, shed light on its putative threats, and realize its opportunities.
The Conundrum of Poor Ovarian Response: From Diagnosis to Treatment
TLDR
This critical review analyzes the standing criteria employed in order to diagnose and aptly categorize POR patients, while it proceeds to critically evaluate current and novel strategies regarding their management.
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