The Bloom's syndrome gene product is a 3'-5' DNA helicase.

@article{Karow1997TheBS,
  title={The Bloom's syndrome gene product is a 3'-5' DNA helicase.},
  author={Julia K. Karow and Ronjon K Chakraverty and Ian D. Hickson},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 49},
  pages={30611-4}
}
Bloom's syndrome (BS) is an autosomal recessive condition characterized by short stature, immunodeficiency, and a greatly elevated frequency of many types of cancer. The gene mutated in BS, BLM, encodes a protein containing seven "signature" motifs conserved in a wide range of DNA and RNA helicases. BLM is most closely related to the subfamily of DEXH box… CONTINUE READING