The Biosynthetic Pathway of Astaxanthin in a Green Alga Haematococcus pluvialis as Indicated by Inhibition with Diphenylamine

@inproceedings{Fan2005TheBP,
  title={The Biosynthetic Pathway of Astaxanthin in a Green Alga Haematococcus pluvialis as Indicated by Inhibition with Diphenylamine},
  author={Lu Fan and Avigad Vonshak and Rachel Gabbay and Joseph Hirshberg and Z. Cohen and Sammy Boussiba},
  year={2005}
}
The effect of diphenylamine on astaxanthin biosynthesis in Haematococcus pluvialis was studied. Cultures induced to produce astaxanthin accumulated ^-carotene in the presence of the inhibitor. It was found that 30 /iM diphenylamine specifically inhibits the biosynthesis of astaxanthin at the step of conversion of /^-carotene to echinenone and canthaxanthin. The results imply that these two compounds are genuine intermediates in the pathway of astaxanthin biosynthesis in H. pluvialis. 

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