The Big Bang of picorna-like virus evolution antedates the radiation of eukaryotic supergroups

  title={The Big Bang of picorna-like virus evolution antedates the radiation of eukaryotic supergroups},
  author={Eugene V. Koonin and Yuri I. Wolf and Keizo Nagasaki and Valerian V. Dolja},
  journal={Nature Reviews Microbiology},
The recent discovery of RNA viruses in diverse unicellular eukaryotes and developments in evolutionary genomics have provided the means for addressing the origin of eukaryotic RNA viruses. The phylogenetic analyses of RNA polymerases and helicases presented in this Analysis article reveal close evolutionary relationships between RNA viruses infecting hosts from the Chromalveolate and Excavate supergroups and distinct families of picorna-like viruses of plants and animals. Thus, diversification… 
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