The Biased Distribution of Alus in Human Isochores Might Be Driven by Recombination

@article{Hackenberg2004TheBD,
  title={The Biased Distribution of Alus in Human Isochores Might Be Driven by Recombination},
  author={Michael Hackenberg and Pedro Bernaola-Galv{\'a}n and Pedro Carpena and Jos{\'e} L. Oliver},
  journal={Journal of Molecular Evolution},
  year={2004},
  volume={60},
  pages={365-377}
}
Alu retrotransposons do not show a homogeneous distribution over the human genome but have a higher density in GC-rich (H) than in AT-rich (L) isochores. However, since they preferentially insert into the L isochores, the question arises: What is the evolutionary mechanism that shifts the Alu density maximum from L to H isochores? To disclose the role played by each of the potential mechanisms involved in such biased distribution, we carried out a genome-wide analysis of the density of the Alus… CONTINUE READING
BETA

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 51 REFERENCES

Similar Papers

Loading similar papers…