| This report describes the Stroke Lesion Segmentation Project of the UMass Computer Vision Laboratory in cooperation with Baystate Medical Center. Its purpose is to deene the current state and next steps, and to familiarize the reader with existing data and tools. After a brief description of the project and its clinical goals, the UMass contributions and possible approaches are presented. Thorough literature reviews are related to our goals. Additional preliminary experiments are discussed. The report concludes with a description of our clinical data and existing tools.