The BLAST Sequence Analysis Tool

  title={The BLAST Sequence Analysis Tool},
  author={Tom Madden},
A sequence similarity search often provides the first information about a new DNA or protein sequence. A search allows scientists to infer the function of a sequence from similar sequences. There are many ways of performing a sequence similarity search, but probably the most popular method is the “Basic Local Alignment Search Tool” (BLAST) (1, 2). BLAST uses heuristics to produce results quickly. It also calculates an “expect value” that estimates how many matches would have occurred at a given… CONTINUE READING