The Average Common Substring Approach to Phylogenomic Reconstruction


We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our method is a new measure of pairwise distances between sequences. This measure is based on computing the average lengths of maximum common substrings, which is intrinsically related… (More)
DOI: 10.1089/cmb.2006.13.336


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